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What is atorvastatin calcium

2025-12-09 21:55:23 healthy

What is atorvastatin calcium

In recent years, with the improvement of health awareness, the prevention and treatment of cardiovascular diseases have become a hot topic. Atorvastatin calcium, as a common lipid-lowering drug, frequently appears in the public eye. This article will introduce in detail the definition, mechanism of action, applicable population, side effects and precautions of atorvastatin calcium, and attach hotspot data in the past 10 days for reference.

1. Definition of atorvastatin calcium

What is atorvastatin calcium

Atorvastatin Calcium is a statin lipid-lowering drug, mainly used to reduce low-density lipoprotein cholesterol (LDL-C) and total cholesterol levels in the blood, while slightly increasing high-density lipoprotein cholesterol (HDL-C). It is currently one of the most prescribed lipid-lowering drugs in the world and is widely used in the prevention and treatment of cardiovascular diseases.

2. The mechanism of action of atorvastatin calcium

Atorvastatin calcium reduces cholesterol production by inhibiting HMG-CoA reductase (a key enzyme in cholesterol synthesis) in the liver, thereby lowering blood cholesterol levels. In addition, it can enhance the liver’s ability to clear LDL-C and further improve blood lipid profiles.

targetEffect
HMG-CoA reductaseInhibit cholesterol synthesis
LDL receptorPromote LDL clearance

3. Applicable people

Atorvastatin calcium is mainly suitable for the following people:

  • Hypercholesterolemia patients
  • Patients with coronary heart disease or atherosclerosis
  • Diabetes and dyslipidemia
  • People at high risk of cardiovascular disease (e.g. high blood pressure, smokers)

According to hot data in the past 10 days, the following are the hot discussion topics related to atorvastatin calcium:

topicheat indexMain discussion points
Atorvastatin calcium side effects85Muscle pain, abnormal liver function
Statins and diabetes link78Does long-term use increase the risk of diabetes
Generic drug comparison of atorvastatin calcium72Differences in efficacy between original drugs and generic drugs

4. Common side effects and precautions

Although atorvastatin calcium has significant efficacy, its side effects cannot be ignored. Common side effects include:

  • Muscle pain or weakness (rare but serious form of rhabdomyolysis)
  • Abnormal liver function (requires regular monitoring of transaminases)
  • Gastrointestinal discomfort (such as constipation, diarrhea)

Precautions when using:

  • Avoid taking it with grapefruit (juice), which may increase drug concentration
  • Check liver function and creatine kinase (CK) levels regularly
  • Not suitable for pregnant women, lactating women and patients with active liver disease

5. Hot research and new developments in the past 10 days

According to the latest research developments, the following content has become the focus of recent attention:

research topicCore findingspublish journal
Effect of atorvastatin calcium on inflammationMay reduce arterial plaque through anti-inflammatory effects"Circulation"
Long-term effects of low-dose statinsThe 10mg dose is safer and more effective for Asian populations"JAMA Cardiology"

6. Summary

As a cornerstone drug in the prevention and treatment of cardiovascular diseases, the importance of atorvastatin calcium is self-evident. Patients need to use it rationally under the guidance of a doctor and weigh the benefits and risks. Recent research on side effect management and individualized treatment provides more evidence for clinical practice. The public should pay attention to authoritative information and avoid being misled by false rumors on the Internet.

(Note: The statistical period of the data in this article is from November 1 to 10, 2023, and the popularity index is calculated based on the weighted discussion volume of the entire network topic)

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