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When to take folic acid during pregnancy

2025-12-12 13:33:34 female

When should you take folic acid during pregnancy? Science Supplement Guide

Folic acid is an essential nutrient during pregnancy and is crucial for fetal neural tube development. Among the pregnancy topics that have been hotly discussed on the Internet recently, the timing of folic acid supplementation has become one of the issues that expectant mothers are most concerned about. This article will give you detailed answers based on popular discussions and authoritative suggestions in the past 10 days.

1. The best time to supplement folic acid

When to take folic acid during pregnancy

According to the consensus of experts in obstetrics and gynecology, folic acid supplementation should be divided into three stages: pre-pregnancy, early pregnancy and middle and late pregnancy:

stagetime rangedaily dosefunction
Pre-pregnancy supplement3 months before planning pregnancy400-800μgreserve folate levels
first trimester1-12 weeks pregnant400-800μgPrevent neural tube defects
second and third trimester13 weeks to delivery400μgSupport continued fetal development

2. Top 5 popular questions and answers

According to recent statistics from major maternal and infant platforms, the most concerning folic acid-related issues are as follows:

Rankingquestionfrequency of occurrence
1What should I do if I don’t take folic acid in advance during an unexpected pregnancy?32.7%
2Can folic acid be taken with calcium tablets?25.4%
3Which is better, natural folic acid or synthetic folic acid?18.9%
4What should I do if my morning sickness worsens after taking folic acid?15.2%
5Do I need to take folic acid during breastfeeding?7.8%

3. Folic acid supplementation programs for different groups of people

According to the latest recommendations from the Chinese Nutrition Society, special groups need to adjust their supplementation plans:

Crowd classificationRecommended dosagereplenishment cycleThings to note
healthy women of childbearing age400μg/day3 months before pregnancy to 3 months of pregnancyRegular supplement
History of childbearing with neural tube defects4-5mg/day1 month before pregnancy to 3 months of pregnancyRequires medical guidance
Diabetic/obese pregnant women1mg/dayPre-pregnancy to deliveryMonitor blood sugar
Epilepsy patients taking medication5mg/dayBefore pregnancy to 12 weeks of pregnancyAntiepileptic drugs need to be adjusted

4. Ranking of foods with folic acid content

In addition to supplements, folic acid in natural foods cannot be ignored. Recent nutritional surveys show that the following foods are rich in folic acid:

foodFolic acid content (μg/100g)Recommended serving size
chicken liver11721-2 times a week
spinach347100g per day
asparagus2623 times a week
Broccoli21050-100g daily
avocado81half a day

5. Latest suggestions from experts (updated in 2023)

1.Time extension:The latest guidelines from the American College of Obstetricians and Gynecologists recommend that folic acid supplementation should be continued until the end of the lactation period because breast milk depletes the mother's folate stores.

2.Dosage adjustment:The British Nutrition Foundation recommends that obese pregnant women (BMI>30) should increase their pre-pregnancy folic acid dose to 5mg/day.

3.Joint supplement:China’s pregnancy health care guidelines emphasize that folic acid should be supplemented with vitamin B12, as the synergistic effect of the two is more beneficial to fetal development.

Summary:Scientific folic acid supplementation requires grasping the "golden trimester" principle, that is, supplementation begins 3 months before pregnancy and continues until the end of the first trimester. Special groups of people need to adjust the dosage according to the doctor's advice and pay attention to dietary supplements. It is recommended that all women preparing for pregnancy undergo folic acid metabolism gene testing and develop a personalized supplement plan.

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